Temephos is an organophosphate larvicide used to treat water infested with disease-carrying insects[2] including mosquitoes, midges, and black fly larvae.
As with other organophosphates, Temephos affects the central nervous system through inhibition of cholinesterase. In larvae, this results in death before reaching the adult stage.
In the developing world where the vector-borne disease dengue fever is endemic, Temephos is widely used and applied by both private and public pest control in areas of standing water where the Aedes aegypti mosquito breeds in order to reduce the population of this disease-carrying insect.Temephos is also used in theGuinea worm eradication program to kill water fleas that carry guinea worm larvae.
Names |
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IUPAC name |
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Other names |
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Identifiers |
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CAS Registry Number |
3383-96-8 |
ChEBI |
CHEBI:38954 |
ChEMBL |
ChEMBL1355821 |
ChemSpider |
5199 |
InChI |
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Jmol-3D images |
Image |
KEGG |
D06062 |
MeSH |
Temefos |
PubChem |
5392 |
SMILES |
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UNII |
ONP3ME32DL |
Properties |
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Chemical formula |
C16H20O6P2S3 |
Molar mass |
466.46 g·mol−1 |
Appearance |
white, crystalline solid |
Density |
1.32 g cm−3 |
Melting point |
30 °C (86 °F; 303 K) |
Boiling point |
120–125 °C (248–257 °F; 393–398 K) (decomposes) |
Solubility in water |
insoluble |
Vapor pressure |
0.00000007 mmHg (20°C) |
Hazards |
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US health exposure limits (NIOSH): |
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PEL (Permissible) |
15 mg/m3 |
REL (Recommended) |
TWA 10 mg/m3 (total) TWA 5 mg/m3 (resp) |
IDLH (Immediate danger |
N.D. |